Progressive multiple sclerosis CSF induces inflammatory demyelination, axonal loss, and astrogliosis in mice
Cristofanilli M, Rosenthal H, Cymring B, Gratch D, Pagano B, Xie B, Sadiq SA.
Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory demyelination and neurodegeneration throughout the CNS, which lead over time to a condition of irreversible functional decline known as progressive MS.
Currently, there are no...
EAE is not a useful model for demyelinating disease<br><br>
Peter O. Behanemail, Abhijit Chaudhuri<br><br>
Experimental allergic encephalomyelitis (EAE) is the commonest, readily induced, organspecific, autoimmune disorder of laboratory animals of its kind. <br><br>
It is an artificial...
Multiple sclerosis in children: an update on clinical diagnosis, therapeutic strategies, and research
Amy Waldman MD, Prof Angelo Ghezzi MD, Amit Bar-Or MD, Yann Mikaeloff MD, Prof Marc Tardieu PhD, Prof Brenda Banwell MD
The clinical features, diagnostic challenges, neuroimaging appearance, therapeutic options, and pathobiological research progress in childhood—and adolescent—onset multiple sclerosis have been informed by many...
New Zealand researchers have been given the green light to trial new treatments on multiple sclerosis patients using anti-psychotic drugs.
The researchers from Victoria University believe they may be able to reduce the symptoms of this debilitating disease using commonly prescribed drugs.
They say a lower dosage of Clozapine and Risperidone, which...
That is the finding of a Monash University study, published in the journal of the Federation of American Societies for Experimental Biology.......