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Lemtrada™ (alemtuzumab)

LEMTRADA is a prescription medicine used to treat adults with relapsing forms of Multiple Sclerosis (MS). Because of its risks, LEMTRADA is generally used in people who have tried 2 or more MS medicines that have not worked well enough. It is not known if LEMTRADA is safe and effective for use in children under 17 years of age.

 

Do not receive LEMTRADA if you are infected with human immunodeficiency virus (HIV).

 

http://products.sanofi.us/Lemtrada/Lemtrada_MedGuide.pdf

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1632 Hits

Avonex FDA- approved

    * weekly low dose interferon

    * for relapsing-remitting MS

    * protects against severe relapses

    * intramuscular injection once a week

    * side effects: flu like symptoms 

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1783 Hits

Betaseron and Extavia (interferon-beta-1b) FDA-approved

    * subcutaneous (under skin) injection every other day

    * interferon

    * for relapsing-remitting, first symptom, and progressive-relapsing MS

    * reduces relapse rate

    * side effects: flu like symptoms, injection site reactions

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1738 Hits

Rebif (interferon-beta-1a) FDA-approved

    * subcutaneous injection three times a week

    * interferon

    * for relapsing-remitting MS

    * reduces relapse rate

    * side effects: flu like symptoms

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1513 Hits

Copaxone (glatiramer acetate) - FDA approved

    * daily subcutaneous injection

    * noninterferon, probably safest medication for MS

    * skin redness, itching, and dimpling common

    * for relapsing-remitting MS and first symptom MS

    * reduces relapse rate

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2070 Hits

Novantrone (mitoxantrone) FDA- approved for MS

    * powerful immunosuppressive medication - rarely used

    * chemotherapy agent

    * for Secondary Progressive, progressive relapsing, and some

       types of relapsing-remitting MS

    * reduces relapses and lengthens time between relapses

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1235 Hits

Tysabri (natalizumab) approved for MS

    * antibody that makes it difficult for immune system cells to

       move into the brain and spinal cord

    * for Relapsing Remitting MS that has not responded

       to other treatment

    * reduces relapse rate

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1275 Hits

Azathioprine (Imuran), leflunomide (Arava), and Methotrexate - not approved for MS

    * immunosuppressive medications in pill form

    * rarely used as therapy at first due to their 

       increased risk 

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1416 Hits

Gilenya (fingolimod) FDA approved

    * mild immunosuppressive/immunomodulatory medication in pill form

    * good safety profile, but some risks require consideration and monitoring

    * first dose usually give in doctors office

    * 1:200 risk of eye (macula) swelling

    * 1:200 risk of symptoms with slow heart rate on first dose

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1108 Hits

Alemtuzumab (CAMPATH)

US Campath Distribution Program

 

The Campath Distribution Program was developed to ensure continued access to Campath® (alemtuzumab) for appropriate patients. Effective September 4, 2012 Campath will no longer be available commercially, but will be provided through the Campath Distribution Program free of charge. In order to receive Campath, the healthcare provider is required to document and comply with certain requirements. Please contact the numbers below to learn more.

 

Important Contact Information

 

Campath Distribution Program: 1-877-422-6728

 

Genzyme Medical Information: 1-800-745-4447 Option #2

http://www.campath.com/

 

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1383 Hits

Rituximab (Rituxan)

    * immunosuppressive iv medication

    * usually used as rescue therapy in very severe MS

    * rarely used as therapy at first due to increased risk 

    * risk of serious infections

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Symptoms of MS and Demyelinating Diseases

symptoms of any disease in the nervous system usually depend on which portion of the nervous system is involved. For example, a problem near the part of the brain involved with sensing movement will be felt as abnormal movement sensation or vertigo. A problem in the pathway carrying vision impulses will produce blurred vision. Trouble in the large bundle of nervous tissue in the neck (the spinal cord) will produce difficulties with sensation difficulties or trouble with the arms, legs, bladder, bowels, or sexual function. Some parts of the brain can be affected and cause few obvious symptoms. For example, the deep white matter of the brain can be affected and produce difficulty with concentration, finding words, or fatigue. Because people with MS have the disease for many years, they often experience similar symptoms as time goes by.

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1263 Hits

Management of Relapses in MS

Relapses will occur to 90% of people with MS at some point. A relapse is usually defined as symptoms which are Worsening over at least 24 hours, presumed to be due to MS, and not due to an infection which is causing a fever. Not all relapses require treatment. The first question is to ask whether one has such an infection prior to considering treatment of a relapse. If a bladder infection is suspected because of an increase in urgency to void, burning on urination, or odor of urine, this must be addressed by an appropriate physician. Milder relapses, such as tingling numbness, mild visual disturbances which do not disrupt reading or driving, or mild vertigo do not usually require treatment and will resolve often spontaneously. Relapses which will usually need treatment are those with significant bowel or bladder dysfunction, major difficulty with walking or balance, or vision loss. Sensation abnormalities which are very painful or involve difficulty using a limb may also benefit. 

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Medications that modify the course of MS

Currently, 5 injectable medications are approved in the US as being safe and effective for MS to reduce relapses and risk of progressive disability. Several pill therapies are also sometimes used. Three injections are different forms of interferon-beta, a hormone used by the body to defend against viruses. One injection is an artificial protein which alters the immune response, much like an allergy shot. The other medications are stronger medications to diminish the action of the immune cells.

 

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1263 Hits

Treatment of symptoms in MS

It is important to emphasize that symptoms of MS are best treated first by finding a therapy which reduces new injuries to the nervous system. However, many treatments are available to help diminish individual symptoms arising from MS. Fatigue, the most common symptom, is often difficult and requires many attempts at treatment. First, the quality of night time sleep is examined. If one does not awake feeling rested, usually the night time sleep is disturbed. Trouble getting to sleep is often helped by a sleep aid, while trouble staying asleep in the middle or latter part of the night usually responds to antidepressant medications. Individuals who snore, or have leg movements frequently, may have very disturbed sleep efficiency resulting in poorly restful sleep.

The most common fatigue in MS is excessive mid or later day fatigue. This may respond to stimulant therapies. An older stimulant, amantadine, or a newer nonnarcotic stimulant called Provigil, are proven therapies in MS. Stronger stimulants of the amphetamine family are sometimes used but require much closer supervision.

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1836 Hits

Why do people get MS?

The best simple answer is "bad luck." A more complete explanation is that why an individual develops MS is due to a combination of factors which elevated risk. In the US, about 1 in 250 people will develop MS. Most of the risk of getting MS has to do with ancestry. Having a close relative with MS elevates the risk 50 times. However, only 2-5% of children of affected parents will be diagnosed with MS. People of Northern European descent, and those who grow up farther from the equator, are more at risk. However, any person can get MS. The risk to African Americans is about ½ of that of Caucasians in the US. Despite this, most people with MS do not have an affected family member. Some families break these rules and have many affected members, but the usual situation is that MS is less of a genetic illness than diabetes, heart disease, Parkinson’s disease, or Alzheimer’s disease.

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2219 Hits

Testing for multiple sclerosis

In most individuals with MS, their diagnosis is established over time and the consideration of alternative causes for their symptoms. One astonishing fact about MS, is that once an individual has a typical problem associated with MS, the risk of having MS within 15 years is 90% even if all other tests show negative findings. The gold standard of diagnosis is seeing multiple problems in the nervous system come and go without another explanation.

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Ethics and Transparency Statement

Social Media and Other Promotional Tools
We participate in social media outlets such as Twitter, Facebook, and Pinterest. We post links to articles to help promote this site in addition to general interest items.

 

Advertising
In an attempt to subsidize both the time invested in this site as well as day to day operations, this site utilizes advertising banners, affiliate links, and automated advertising mechanisms.

We use affiliate links within actual articles. Also some of the RSS feeds we use to help provide information may have affiliate links that we have no control over, and are not controlled by us.

We do use services such as Amazon to help gather funds to keep this website up and running.

 

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Terms and Conditions for Using MSChristian.org

Terms and Conditions for Using MSChristian.org

Welcome to MSChristian.org. If you continue to browse and use this website you are agreeing to comply with and be bound by the following terms and conditions of use, which together with our privacy policy govern MSChristian's relationship with you in relation to this website.

The term 'MSC or 'us' or 'we' refers to the MSChristian.org website.  The term 'you' refers to the user or viewer of our website.

The use of this website is subject to the following terms of use:

The content of the pages of this website is for your general information and use only. It is subject to change without notice.
Neither we nor any third parties provide any warranty or guarantee as to the accuracy, timeliness, performance, completeness or suitability of the information and materials found or offered on this website for any particular purpose. You acknowledge that such information and materials may contain inaccuracies or errors and we expressly exclude liability for any such inaccuracies or errors to the fullest extent permitted by law.
Your use of any information or materials on this website is entirely at your own risk, for which we shall not be liable. It shall be your own responsibility to ensure that any information available through this website meet your specific requirements.
This website contains material which is owned by or licensed to us. This material includes, but is not limited to, the design, layout, look, appearance and graphics. Reproduction is prohibited other than in accordance with the copyright notice, which forms part of these terms and conditions.
All trade marks reproduced in this website which are not the property of, or licensed to, the operator are acknowledged on the website.
Unauthorized use of this website may give rise to a claim for damages and/or be a criminal offense.
From time to time this website may also include links to other websites. These links are provided for your convenience to provide further information. They do not signify that we endorse the website(s). We have no responsibility for the content of the linked website(s).
Links to content within this website is encouraged although restructuring of the site's architecture may render some links Inactive. It is not MSChristian's responsibility to inform you of any changes to our architecture.
Your use of this website and any dispute arising out of such use of the website is subject to the laws of the United States of America.

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Indiana law for religious freedom and does MSChristian.org or NSMinistries.com support it

Alright since I am getting bombarded with questions pertaining to the Indiana law for religious freedom and does MSChristian.org or NSMinistries.com support it, I want to have a onetime say on it. (This is mostly for my Facebook page.)

MSChristian.org and NSMinistries.com are Christian organizations. That being said we and myself do not believe homosexuality is right in the eyes of God, but we will not judge or turn anyone away for being gay, transgender, or otherwise not straight. This is a matter for that individual and God to hash out. MSC, NSM, and I are not going to judge or debate that matter. If asked I will give my opinion as I feel I have a right to do.

All these so called Christian’s that are judging need to take a step back and re-evaluate their position as well in our opinion. Stating an opinion is one thing but acting on something we were never told to do in the Bible, (the fulfilled law and commandments set forth by the New Testament, and Old Testament as fulfilled or brought forward with the teachings of the New Testament Church), is a line that we are not willing to cross. Unless there is a new prophet out there that I don’t know about, (yes that is sarcasm), judging others before taking the plank out of your own eye is just plain folly.

Addressing religious people either of the Christian faith or others remember you live in a country with freedoms that extend to even those not of a faith. I cannot and will not express an opinion to faiths that are not Christian on the matter. To Christian’s remember you cannot expect others that are not Christian to hold the same values and beliefs Christian’s do. Most of the time most Christian’s cannot agree on what those values and beliefs are any way.

To those supporting the law in Indiana if you are going to support it do it consistently at least. Check on your suppliers and other aspects of your business and follow suit with them as well. Being on the fence by choosing to take products, supplies, and monies from those that do support gay rights puts you on the fence, and remember how Jesus felt about that. Example for all you to take to heart, can you justify accepting Visa card even though they have programs that help support gay rights? Yes I can back up the claim, check out this link: http://www.hrc.org/support/get-an-hrc-visa-card. And just to make sure no one is reading this the wrong way I have no opinion one way or the other on this as we daily have to choose how we will live our lives and please re-read the above statement.

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