Assuming cells is required, the following results were found.

  • Forgotten immune cells protective in mouse model of multiple sclerosis

    A seldom-studied class of immune cells may reduce the friendly fire that drives autoimmune disease, according to a new study by researchers at the Stanford University School of Medicine. Stimulating these protective cells could lead to new therapies...

    https://mschristian.org/index.php/blog/forgotten-immune-cells-protective-in-mouse-model-of-multiple-sclerosis
  • Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2 - Science

    homozygous missense Arg148Trp variant in STAT2, a transcription factor that functions exclusively downstream of innate IFNs. Cells bearing STAT2R148W in homozygosity (but not heterozygosity) were hypersensitive to IFNα/β, which manifest as prolonged...

    https://mschristian.org/index.php/blog/severe-type-i-interferonopathy-and-unrestrained-interferon-signaling-due-to-a-homozygous-germline-mutation-in-stat2-science
  • B cells among factors leading to brain lesions in multiple sclerosis

    of ZurichSummary:A team of researchers has shown that in multiple sclerosis, it is not only specific T cells that cause inflammation and lesions in the brain. B cells, a different type of immune cell, also play a role. These cells activate T cells in...

    https://mschristian.org/index.php/blog/b-cells-among-factors-leading-to-brain-lesions-in-multiple-sclerosis
  • Cellular metabolism regulates the fate decision between pathogenic and regulatory T cells: Manipulating cellular metabolism may provide a promising therapeutic intervention in autoimmune diseases - Science Daily

    sclerosis, inflammatory bowel disease and rheumatoid arthritis have an imbalance between two types of immune system T cells. Destructive Th17 cells that mediate chronic inflammation are elevated, and regulatory T cells, or Treg cells, which suppress...

    https://mschristian.org/index.php/blog/cellular-metabolism-regulates-the-fate-decision-between-pathogenic-and-regulatory-t-cells-manipulating-cellular-metabolism-may-provide-a-promising-therapeutic-intervention-in-autoimmune-diseases-science-daily
  • Nature of immune cells in the human brain disclosed

    Date:Source:Netherlands Institute for Neuroscience - KNAWSummary:Researchers have disclosed the nature of how T cells protect the brain against harmful viruses. The results of the study are important for investigating the role of the immune system in...

    https://mschristian.org/index.php/blog/nature-of-immune-cells-in-the-human-brain-disclosed
  • Multiple sclerosis: Helping cells to help themselves

    such as multiple sclerosis are characterized by damage to the 'myelin sheath', a protective covering wrapped around nerve cells akin to insulation around an electrical wire. Researchers have discovered how the body initiates repair mechanisms which will...

    https://mschristian.org/index.php/blog/multiple-sclerosis-helping-cells-to-help-themselves
  • MS Progression Stopped by Targeting T Helper Cells with CXCR6 Receptor in Mouse Model - Multiple Sclerosis News Today

    Targeting the chemokine receptor CXCR6, a protein at the surface of a certain group of T helper cells, prevented the development of multiple sclerosis (MS) in a mouse model of the disease, a study reports. Its findings suggest that antibodies targeting...

    https://mschristian.org/index.php/blog/ms-progression-stopped-by-targeting-t-helper-cells-with-cxcr6-receptor-in-mouse-model-multiple-sclerosis-news-today
  • New clues to the origin and progression of multiple sclerosis

    Mapping of a certain group of cells, known as oligodendrocytes, in the central nervous system of a mouse model of multiple sclerosis (MS), shows that they might have a significant role in the development of the disease. The discovery can lead to new...

    https://mschristian.org/index.php/blog/new-clues-to-the-origin-and-progression-of-multiple-sclerosis
  • Fooling nerve cells into acting normal

    Credit: © peterschreiber.media / Adobe Stock Nerve cell illustration. Credit: © peterschreiber.media / Adobe Stock Nerve cells, or neurons -- specifically the "workhorse cells" involved in walking, breathing and chewing -- can adjust to changes in the...

    https://mschristian.org/index.php/blog/fooling-nerve-cells-into-acting-normal
  • Boston Children's Hospital researchers seem to have pinpointed the cause of multiple sclerosis

    It’s been known for quite some time that multiple sclerosis (MS) and other autoimmune diseases are driven by angry helper T cells (T lymphocytes) that somehow mistake your own tissues for an invader that needs to be attacked. People with MS, in a sense,...

    https://mschristian.org/index.php/blog/boston-children-s-hospital-researchers-seem-to-have-pinpointed-the-cause-of-multiple-sclerosis
  • Multiple Doses of Stem Cells Show Potential in Treating Severe Asthma - Yahoo Finance

    and Technology for Regenerative Medicine describe how multiple doses of a type of stem cell called mesenchymal stromal cells (MSCs) might offer a new way to treat people suffering from severe asthma. Results were reported in STEM CELLS Translational...

    https://mschristian.org/index.php/blog/multiple-doses-of-stem-cells-show-potential-in-treating-severe-asthma-yahoo-finance
  • A Surprising Contributor to Multiple Sclerosis - Technology Networks

    Cells that scientists have largely ignored when studying multiple sclerosis are actually key contributors to MS development, new research from the School of Medicine shows. The discovery suggests new avenues for devising treatments and is a vital step...

    https://mschristian.org/index.php/blog/a-surprising-contributor-to-multiple-sclerosis-technology-networks
  • Rejuvenating brain stem cells may hold key to future MS treatments

    Scientists have found a way to make older brain stem cells in rats more youthful. The discovery could lead to improved treatments for aging-related diseases that degrade the brain and nervous system. Researchers managed to rejuvenate stem cells,...

    https://mschristian.org/index.php/blog/rejuvenating-brain-stem-cells-may-hold-key-to-future-ms-treatments
  • Studies Report on Efforts to Optimize Rituximab in MS, NMOSD - The Center for Biosimilars

    Medical Center Göttingen, in Göttingen, Germany, presented findings on their study on the phenotype and function of B cells that reappear after treatment with rituximab.1 The researchers assessed peripheral blood mononuclear cells of 15 patients with...

    https://mschristian.org/index.php/blog/studies-report-on-efforts-to-optimize-rituximab-in-ms-nmosd-the-center-for-biosimilars
  • Newly discovered immune cells play role in inflammatory brain diseases

    -- University of Freiburg has succeeded in demonstrating in an animal model that previously entirely unknown types of immune cells are present in the inflamed brain in the course of multiple sclerosis (MS). The discovery was made by means of a new,...

    https://mschristian.org/index.php/blog/newly-discovered-immune-cells-play-role-in-inflammatory-brain-diseases
  • Potential genetic markers of multiple sclerosis severity

    and severity of MS, an unpredictable disorder in which the immune system eats away at protective insulation around nerve cells. This approach, the researchers say, represents the beginning of precision medicine for MS and may ultimately allow designer...

    https://mschristian.org/index.php/blog/potential-genetic-markers-of-multiple-sclerosis-severity
  • How the gut influences neurologic disease

    diseases. Investigators from Brigham and Women's Hospital (BWH) have been using both animal models and human cells from patients to tease out the key players involved in the gut-brain connection as well as in the crosstalk between immune cells and brain...

    https://mschristian.org/index.php/blog/how-the-gut-influences-neurologic-disease
  • Study sheds light on brain cell changes in people with MS

    Fresh insights into the types of cells found in the brains of people with multiple sclerosis could help develop improved therapies, research has found. The study focused on cells in the brain that help to repair damage to nerve cells caused by the...

    https://mschristian.org/index.php/blog/study-sheds-light-on-brain-cell-changes-in-people-with-ms
  • Researchers Identify Nerve Cells That Are Vulnerable to Damage in MS

    in Cambridge and San Francisco used advanced technology to evaluate genetic instructions within single brain cells in specific areas of brain tissues from people who had MS in their lifetimes, before there were disease-modifying therapies.They report...

    https://mschristian.org/index.php/blog/researchers-identify-nerve-cells-that-are-vulnerable-to-damage-in-ms
  • How childhood viral infections may later drive multiple sclerosis

    For the second step of the research, the investigators allowed all the mice to age. Then, they transferred self-reactive cells to the mice. This type of cell, the researchers explain, can impact brain structure, and some scientists also believe that...

    https://mschristian.org/index.php/blog/how-childhood-viral-infections-may-later-drive-multiple-sclerosis

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