Assuming key is required, the following results were found.

  • Novartis ofatumumab demonstrates superiority versus Aubagio® in two head-to-head Phase III multiple sclerosis studies

    to reduce the annualized relapse rate over Aubagio®* (teriflunomide) in patients with relapsing forms of MS (RMS)[1] Key secondary endpoints of delaying time to confirmed disability progression were also met[1]; additional secondary endpoints will be...

    https://mschristian.org/index.php/blog/novartis-ofatumumab-demonstrates-superiority-versus-aubagio-in-two-head-to-head-phase-iii-multiple-sclerosis-studies-1
  • Novartis ofatumumab demonstrates superiority versus Aubagio® in two head-to-head Phase III multiple sclerosis studies

    endpoints to reduce the annualized relapse rate over Aubagio®*(teriflunomide) in patients with relapsing forms of MS (RMS)[1] Key secondary endpoints of delaying time to confirmed disability progression were also met[1]; additional secondary endpoints...

    https://mschristian.org/index.php/blog/novartis-ofatumumab-demonstrates-superiority-versus-aubagio-in-two-head-to-head-phase-iii-multiple-sclerosis-studies
  • #ECTRIMS2019 - Mayzent's Benefits for MS Patients a 'Key Question,' Says EXPAND's Principal Investigator - Multiple Sclerosis News Today

    MS (RRMS) and active secondary progressive MS (SPMS). Data from the EXPAND study (NCT01665144) was one of the key pieces of evidence for Mayzent’s approval. Involving 1,651 patients with SPMS (both active and non-active), the study showed that taking 2...

    https://mschristian.org/index.php/blog/ectrims2019-mayzent-s-benefits-for-ms-patients-a-key-question-says-expand-s-principal-investigator-multiple-sclerosis-news-today
  • Disability progression in multiple sclerosis linked to income, education

    that lower neighbourhood-level income and educational attainment was associated with an increased likelihood of reaching key physical disability milestones, such as difficulties with walking. The findings -- published online today in Neurology®, the...

    https://mschristian.org/index.php/blog/disability-progression-in-multiple-sclerosis-linked-to-income-education
  • Rejuvenating brain stem cells may hold key to future MS treatments

    Scientists have found a way to make older brain stem cells in rats more youthful. The discovery could lead to improved treatments for aging-related diseases that degrade the brain and nervous system. Researchers managed to rejuvenate stem cells,...

    https://mschristian.org/index.php/blog/rejuvenating-brain-stem-cells-may-hold-key-to-future-ms-treatments
  • Food allergies and multiple sclerosis: New link

    the mechanism of multiple sclerosis remains an enigma -- a puzzle composed of complex genetic and environmental factors. A key piece to this puzzle is the immune system, which is also responsible for regulating many other physiological (and...

    https://mschristian.org/index.php/blog/food-allergies-and-multiple-sclerosis-new-link
  • AAN publishes new guideline on vaccinations for people with multiple sclerosis

    We reviewed all of the available evidence and for people with MS, preventing infections through vaccine use is a key part of medical care. People with MS should feel safe and comfortable getting their recommended vaccinations." Guideline lead author...

    https://mschristian.org/index.php/blog/aan-publishes-new-guideline-on-vaccinations-for-people-with-multiple-sclerosis
  • Genentech to Present Pivotal Data for Satralizumab in Neuromyelitis Optica Spectrum Disorder and Six-year Ocrevus (Ocrelizumab) Data in Multiple Sclerosis at ECTRIMS

    and head of Global Product Development. “Similar to our approach with Ocrevus in multiple sclerosis, targeting B cells as a key driver of disease, we aim to offer satralizumab as a highly effective treatment option in neuromyelitis optica spectrum...

    https://mschristian.org/index.php/blog/genentech-to-present-pivotal-data-for-satralizumab-in-neuromyelitis-optica-spectrum-disorder-and-six-year-ocrevus-ocrelizumab-data-in-multiple-sclerosis-at-ectrims
  • Research on immune activity in MS

    mice with an MS-like disease. The team used a harmless virus to deliver a gene coding for a specific component of myelin, a key target of immune attacks in MS. Further research is needed to verify and refine this approach before it can be tested in...

    https://mschristian.org/index.php/blog/research-on-immune-activity-in-ms
  • How Your Genes and Environment Affect MS

    to a diagnosis of multiple sclerosis (MS). Viral infections and tobacco smoking are two major triggers of the disease. Key environmental factors usually occur before age 15. And factors that cause the onset of MS may differ from those that cause its...

    https://mschristian.org/index.php/blog/how-your-genes-and-environment-affect-ms
  • AJMC® in the Press, September 13, 2019 - AJMC.com Managed Markets Network

    Progressive Multiple Sclerosis” was highlighted by Multiple Sclerosis News Today. The video series, which features multiple key opinion leaders, includes discussions on the nature and cost of multiple sclerosis, debates on whether it is truly an...

    https://mschristian.org/index.php/blog/ajmc-in-the-press-september-13-2019-ajmc-com-managed-markets-network
  • Genentech’s Satralizumab Significantly Reduced Relapse Risk in Second Positive Phase III Study for Neuromyelitis Optica Spectrum Disorder

    to placebo in two Phase III studies across a broad population Satralizumab targets the interleukin-6 (IL-6) receptor, a key driver of NMOSD South San Francisco, CA -- September 11, 2019 -- Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX:...

    https://mschristian.org/index.php/blog/genentech-s-satralizumab-significantly-reduced-relapse-risk-in-second-positive-phase-iii-study-for-neuromyelitis-optica-spectrum-disorder
  • Nature of immune cells in the human brain disclosed

    disorders. Immune system The immune system protects the body against infections and cancer. The so-called T cells play a key role in this process. When T cells do not work properly, an inflammation can develop in for example the brain. Until recently,...

    https://mschristian.org/index.php/blog/nature-of-immune-cells-in-the-human-brain-disclosed
  • B cells among factors leading to brain lesions in multiple sclerosis

    Zurich (UZH), the University Hospital Zurich (USZ) and researchers at the Karolinska Institute in Sweden has now discovered a key aspect in the pathogenesis of MS. "We were able to show for the first time that certain B cells -- the cells of the immune...

    https://mschristian.org/index.php/blog/b-cells-among-factors-leading-to-brain-lesions-in-multiple-sclerosis
  • A Surprising Contributor to Multiple Sclerosis - Technology Networks

    Cells that scientists have largely ignored when studying multiple sclerosis are actually key contributors to MS development, new research from the School of Medicine shows. The discovery suggests new avenues for devising treatments and is a vital step...

    https://mschristian.org/index.php/blog/a-surprising-contributor-to-multiple-sclerosis-technology-networks
  • MS Symptoms - Learn to recognize and manage the possible symptoms of MS, which range from mild to severe.

    MS Keywords: Fatigue; Pain; Gait (Walking), Cognition; Bladder, Bowel, Vision, Sexual Problems and Depression MS symptoms are variable and unpredictable. No two people have exactly the same symptoms, and each person’s symptoms can change or fluctuate...

    https://mschristian.org/index.php/blog/ms-symptoms-learn-to-recognize-and-manage-the-possible-symptoms-of-ms-which-range-from-mild-to-severe
  • Coping with dual diagnoses -- How to prioritize when MS is only one of your health concerns.

    249 earlier studies on MS and other medical conditions, Dr. Marrie’s team published seven papers in the MS Journal in 2015. Key findings include: The five most prevalent disorders that occur alongside MS are depression, anxiety, high blood pressure,...

    https://mschristian.org/index.php/blog/coping-with-dual-diagnoses-how-to-prioritize-when-ms-is-only-one-of-your-health-concerns
  • MS Mindshift Effort Arrives at Atlanta Area's Owl-O-Ween Hot Air Balloon Festival - Multiple Sclerosis News Today

    (MSAA) to promote solidarity with and support those affected by MS. Its main goal is to educate people about the brain’s key role in MS, and to help those with the disease keep their brain as healthy as possible for as long as they can. Similar to a hot...

    https://mschristian.org/index.php/blog/ms-mindshift-effort-arrives-at-atlanta-area-s-owl-o-ween-hot-air-balloon-festival-multiple-sclerosis-news-today
  • #ECTRIMS2019 - Are Injectables Inappropriate for Active Relapsing MS? - Multiple Sclerosis News Today

    disability progression, treatment resistance, and health-related quality of life. Use from the start Early intervention is key. “We really have a window of opportunity,” Kobelt said. “The disease starts even before we can see anything,” and quality of...

    https://mschristian.org/index.php/blog/ectrims2019-are-injectables-inappropriate-for-active-relapsing-ms-multiple-sclerosis-news-today
  • MS Progression Stopped by Targeting T Helper Cells with CXCR6 Receptor in Mouse Model - Multiple Sclerosis News Today

    They first observed that in mice with experimental autoimmune encephalomyelitis (EAE), a condition that mimics key pathological features of MS in humans, a subset of CD4 positive T-cells had high levels of Sb1, along with Rorc and IL17a, two...

    https://mschristian.org/index.php/blog/ms-progression-stopped-by-targeting-t-helper-cells-with-cxcr6-receptor-in-mouse-model-multiple-sclerosis-news-today

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