Assuming loss is required, the following results were found.

  • Tecfidera (dimethyl fumarate)

    a small number of people, they may become severe and indicate liver damage. Symptoms of liver damage can include: fatigue loss of appetite yellowing of your skin or the whites of your eyes Before and throughout your treatment with Tecfidera, your doctor...

    https://mschristian.org/index.php/blog/tecfidera-dimethyl-fumarate
  • Atara Biotherapeutics Announces Third Quarter 2019 Financial Results and Recent Clinical, Operational and Strategic Progress - BioSpace

    cash equivalents and short-term investments are sufficient to fund planned operations into 2021 The Company reported a net loss of $71.9 million, or $1.31 per share, for the third quarter of 2019 as compared to $58.4 million, or $1.29 per share, for the...

    https://mschristian.org/index.php/blog/atara-biotherapeutics-announces-third-quarter-2019-financial-results-and-recent-clinical-operational-and-strategic-progress-biospace
  • Aubagio (teriflunomide)

    More common side effects The more common sideeffects of Aubagio can include: headache alopecia (hair thinning or hair loss) decreased phosphate levels decreased levels of white blood cells nausea diarrhea increased levels of liver enzymes (can be a sign...

    https://mschristian.org/index.php/blog/aubagio-teriflunomide
  • How new gene discoveries could guide precision medicine in multiple sclerosis

    by Arlene Weintraub | Oct 31, 2019 10:20am Variants in three "complement" genes are closely associated with vision loss in multiple sclerosis, Johns Hopkins Medicine researchers discovered. (Pixabay) The most severe form of multiple sclerosis, called...

    https://mschristian.org/index.php/blog/how-new-gene-discoveries-could-guide-precision-medicine-in-multiple-sclerosis
  • Potential genetic markers of multiple sclerosis severity

    say they have identified three so-called "complement system" genes that appear to play a role in MS-caused vision loss. The researchers were able to single out these genes -- known to be integral in the development of the brain and immune systems -- by...

    https://mschristian.org/index.php/blog/potential-genetic-markers-of-multiple-sclerosis-severity
  • Researchers identify genes linked to most severe symptoms of multiple sclerosis

    say they have identified three so-called "complement system" genes that appear to play a role in MS-caused vision loss. The researchers were able to single out these genes -- known to be integral in the development of the brain and immune systems -- by...

    https://mschristian.org/index.php/blog/researchers-identify-genes-linked-to-most-severe-symptoms-of-multiple-sclerosis
  • How does MS affect the eyes?

    problems are relatively common in people with multiple sclerosis and can include blurred sight, double vision, and vision loss. Multiple sclerosis treatments can help. As with the other symptoms of multiple sclerosis (MS), eye symptoms can appear during...

    https://mschristian.org/index.php/blog/how-does-ms-affect-the-eyes-1
  • Novel subtype of multiple sclerosis

    a research team led by Bruce Trapp, Ph.D., identified for the first time a subtype of the disease that features neuronal loss but no demyelination of the brain's white matter. The findings, published in Lancet Neurology, could potentially lead to more...

    https://mschristian.org/index.php/blog/novel-subtype-of-multiple-sclerosis
  • Economic Factors Amplify Burden of Disease for Patients With Multiple Sclerosis

    for people with MS is related to reduced quality of life through physical suffering, limitations imposed on daily life, loss of work, and anxiety about the future." Economic factors may include loss of income for the patient, care-giving time for the...

    https://mschristian.org/index.php/blog/economic-factors-amplify-burden-of-disease-for-patients-with-multiple-sclerosis
  • Stroke drug may also prevent Alzheimer's disease

    protects the brains of mice with Alzheimer's-like symptoms, reducing the buildup of toxic peptides and preventing memory loss. FULL STORY Researchers from the University of Southern California have discovered that a drug currently being developed to...

    https://mschristian.org/index.php/blog/stroke-drug-may-also-prevent-alzheimer-s-disease
  • Everything you need to know about syringomyelia

    and legs that worsens with time pain in the neck and shoulders numbness, tingling, or burning sensations a decrease in or loss of sensitivity to hot and cold, particularly in the hands stiffness and lack of coordination in the legs scoliosis, which is a...

    https://mschristian.org/index.php/blog/everything-you-need-to-know-about-syringomyelia
  • Aerobic Exercise Helps Multiple Sclerosis—But How and How Fast?

    function. A minority of affected individuals have a progressive course from onset. MS symptoms can include weakness, sensory loss, imbalance, incoordination, vision loss, brainstem dysfunction manifesting in double vision and difficulty swallowing,...

    https://mschristian.org/index.php/blog/aerobic-exercise-helps-multiple-sclerosis-but-how-and-how-fast
  • Treatment of symptoms in MS

    control. Antispasmodic medication for the bladder can reduce this, but can lead to difficulty emptying in some cases. Loss of urine involuntarily, or urinary incontinence, can occur for either because of failing to empty or from overactive reflexes, and...

    https://mschristian.org/index.php/articles/ms-and-demyelinating-diseases/11-treatment-of-symptoms-in-ms
  • Newly discovered leukodystrophy in children: Potential cure

    DEGS1 function was generated in the laboratory of Dr Cristina Pujades, UPF Barcelona, and exhibited swimming difficulties, loss of myelin forming cells (oligodendrocytes) and ceramide imbalances. These defects were corrected by a treatment with...

    https://mschristian.org/index.php/blog/newly-discovered-leukodystrophy-in-children-potential-cure
  • Rejuvenating brain stem cells may hold key to future MS treatments

    the aged OPCs began to function like youthful OPCs. Stiffening of stem cell niche The team eventually established that the loss of function in the OPCs was a result of something happening in their microenvironment, or stem cell "niche." "Here we show,"...

    https://mschristian.org/index.php/blog/rejuvenating-brain-stem-cells-may-hold-key-to-future-ms-treatments
  • #ECTRIMS2019 - Mayzent's Benefits for MS Patients a 'Key Question,' Says EXPAND's Principal Investigator - Multiple Sclerosis News Today

    also decreased the annualized relapse rate by 55%, reduced the progression of brain lesions, and lessened whole-brain volume loss (brain atrophy), measured in the overall population (active and non-active SPMS); a further analysis demonstrated an...

    https://mschristian.org/index.php/blog/ectrims2019-mayzent-s-benefits-for-ms-patients-a-key-question-says-expand-s-principal-investigator-multiple-sclerosis-news-today
  • Multiple sclerosis: Perilous ruptures

    of the central nervous system. The degree of the patient´s disability, is critically dependent on the extent of nerve-fiber loss. This is because the autoimmune reaction characteristic of the condition attacks the long processes, called axons, which are...

    https://mschristian.org/index.php/blog/multiple-sclerosis-perilous-ruptures
  • Blood neurofilament light chain as a biomarker of MS disease activity and treatment response

    T2 lesions (ratio of mean: 2.64 [1.51–4.60]; p = 0.0006), relapses (rate ratio: 2.53 [1.67–3.83]; p < 0.0001), brain volume loss (difference in means: −0.78% [−1.02 to −0.54]; p...

    https://mschristian.org/index.php/blog/blood-neurofilament-light-chain-as-a-biomarker-of-ms-disease-activity-and-treatment-response
  • What to know about optic neuritis and MS

    the eye, leading to optic neuritis. Symptoms of optic neuritis include vision problems, painful eyes, and temporary vision loss. Multiple sclerosis (MS) can cause inflammation and damage to the myelin sheath in the optic nerve. This damage is called...

    https://mschristian.org/index.php/blog/what-to-know-about-optic-neuritis-and-ms
  • Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years

    than in those who remained clinically stable. Serum neurofilament light chain level was associated with brain fraction loss, whereas this was less the case for clinical outcomes such as relapses or EDSS worsening. Meaning The association of serum...

    https://mschristian.org/index.php/blog/association-between-serum-neurofilament-light-chain-levels-and-long-term-disease-course-among-patients-with-multiple-sclerosis-followed-up-for-12-years

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