Assuming positive is required, the following results were found.

  • Novartis receives positive CHMP opinion for Mayzent® (siponimod) for the treatment of adult patients with active secondary progressive multiple sclerosis (SPMS) | Small Molecules | News Channels - PipelineReview.com

    Novartis receives positive CHMP opinion for Mayzent® (siponimod) for the treatment of adult patients with active secondary progressive multiple sclerosis (SPMS) DetailsHits: 158If approved, Mayzent® (siponimod) will be the first and only oral treatment...

    https://mschristian.org/index.php/blog/novartis-receives-positive-chmp-opinion-for-mayzent-siponimod-for-the-treatment-of-adult-patients-with-active-secondary-progressive-multiple-sclerosis-spms-small-molecules-news-channels-pipelinereview-com
  • Utah state lawmaker says 84% of vapor products in Salt Lake County tested positive for opioids

    12, 2019 According to a story on fox13now.com, 84 percent of e-cigarette liquid sold in Salt Lake County vape shops tested positive for opioids and other illegal drugs, according to Utah State Rep. Paul Ray. The Davis County Republican said Wednesday...

    https://mschristian.org/index.php/blog/utah-state-lawmaker-says-84-of-vapor-products-in-salt-lake-county-tested-positive-for-opioids
  • Novartis ofatumumab demonstrates superiority versus Aubagio® in two head-to-head Phase III multiple sclerosis studies

    additional secondary endpoints will be presented at ECTRIMS Ofatumumab, a potent, fully-human antibody targeting CD20 positive B-cells, delivered sustained efficacy with a favorable safety profile[1] Novartis plans to initiate submissions to health...

    https://mschristian.org/index.php/blog/novartis-ofatumumab-demonstrates-superiority-versus-aubagio-in-two-head-to-head-phase-iii-multiple-sclerosis-studies-1
  • Novartis ofatumumab demonstrates superiority versus Aubagio® in two head-to-head Phase III multiple sclerosis studies

    additional secondary endpoints will be presented at ECTRIMS #Ofatumumab, a potent, fully-human antibody targeting CD20 positive B-cells, delivered sustained efficacy with a favorable safety profile[1] #Novartis plans to initiate submissions to health...

    https://mschristian.org/index.php/blog/novartis-ofatumumab-demonstrates-superiority-versus-aubagio-in-two-head-to-head-phase-iii-multiple-sclerosis-studies
  • Positive Phase III Results for Genentech’s Satralizumab in Neuromyelitis Optica Spectrum Disorder Published in the New England Journal of Medicine

    disorder (NMOSD), were published in the November 27, 2019 online issue of the New England Journal of Medicine (NEJM). “The positive results from the pivotal SAkuraSky study of satralizumab support the hypothesis that IL-6 plays a key role in NMOSD,...

    https://mschristian.org/index.php/blog/positive-phase-iii-results-for-genentech-s-satralizumab-in-neuromyelitis-optica-spectrum-disorder-published-in-the-new-england-journal-of-medicine
  • Genentech’s Satralizumab Significantly Reduced Relapse Risk in Second Positive Phase III Study for Neuromyelitis Optica Spectrum Disorder

    versus placebo in people with neuromyelitis optica spectrum disorder (NMOSD) with aquaporin-4 antibodies (AQP4-IgG seropositive patients) Satralizumab demonstrated a similar safety profile compared to placebo in two Phase III studies across a broad...

    https://mschristian.org/index.php/blog/genentech-s-satralizumab-significantly-reduced-relapse-risk-in-second-positive-phase-iii-study-for-neuromyelitis-optica-spectrum-disorder
  • Pregnancy & MS - Considerations before starting a family

    In my final semester of graduate school, I became pregnant. My husband and I were overjoyed. My pregnancy was very positive. I embraced the emotions and moments of that time. We took pictures every week of my growing belly and settled on the name Jacob...

    https://mschristian.org/index.php/blog/pregnancy-ms-considerations-before-starting-a-family
  • MS Progression Stopped by Targeting T Helper Cells with CXCR6 Receptor in Mouse Model - Multiple Sclerosis News Today

    “SerpinB1 controls encephalitogenic T helper cells in neuroinflammation” was published in the journal PNAS. Immune CD4 positive T-cells, known as T helper cells, play an important role in the autoimmune reaction against myelin (the protective coat...

    https://mschristian.org/index.php/blog/ms-progression-stopped-by-targeting-t-helper-cells-with-cxcr6-receptor-in-mouse-model-multiple-sclerosis-news-today
  • Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2 - Science

    of STAT2R148W pathomechanism. (D) Modeling of exposed WT (R148)/mutant (W148) residue, demonstrating charge-change (blue, positive; red, negative) and possible steric restriction. (E) Coimmunoprecipitation of USP18 by STAT2 in U6A cells expressing...

    https://mschristian.org/index.php/blog/severe-type-i-interferonopathy-and-unrestrained-interferon-signaling-due-to-a-homozygous-germline-mutation-in-stat2-science
  • Conceptual framework to study role of exercise in multiple sclerosis

    of exercise in various clinical populations, but little attention is being focused on the neural mechanisms that underlie positive changes in mobility and cognition. Using this conceptual framework will enable scientists to systematically examine the...

    https://mschristian.org/index.php/blog/conceptual-framework-to-study-role-of-exercise-in-multiple-sclerosis
  • Dennis Lee Johnson -- Rochester - PostBulletin.com

    Croix. Dennis spent most of his adult life living with multiple sclerosis. He became an inspiration to many because of his positive attitude, great smile, and determination to keep doing the things he loved. He taught in Farmington, Pine Island and...

    https://mschristian.org/index.php/blog/dennis-lee-johnson-rochester-postbulletin-com
  • SPMS and Diet: What Foods Can Help?

    progression of the autoimmune disease. An anti-inflammatory diet also may slow disease progression, as well as enhance the positive effects of anti-inflammatory medications. In MS, the immune system mistakenly attacks the protein coat that surrounds...

    https://mschristian.org/index.php/blog/spms-and-diet-what-foods-can-help
  • Vitamin D no defense against dementia

    agent. "Our work counters an emerging belief held in some quarters suggesting that higher levels of vitamin D can impact positively on brain health," says lead author Krystal Iacopetta, PhD candidate at the University of Adelaide. Based on a systematic...

    https://mschristian.org/index.php/blog/vitamin-d-no-defense-against-dementia
  • MS: Paleo diet may reduce fatigue by improving cholesterol

    based diet can improve exhaustion in people with relapsing remitting MS. New research aimed to investigate whether such positive effects were down to a change in lipid profile and cholesterol. Murali Ramanathan, Ph.D. — a professor in the University of...

    https://mschristian.org/index.php/blog/ms-paleo-diet-may-reduce-fatigue-by-improving-cholesterol
  • Genentech to Present Pivotal Data for Satralizumab in Neuromyelitis Optica Spectrum Disorder and Six-year Ocrevus (Ocrelizumab) Data in Multiple Sclerosis at ECTRIMS

    conditions such as multiple sclerosis and neuromyelitis optica spectrum disorder. Data being presented at ECTRIMS include positive Phase III results for satralizumab as a monotherapy, taking a novel approach to treating neuromyelitisoptica spectrum...

    https://mschristian.org/index.php/blog/genentech-to-present-pivotal-data-for-satralizumab-in-neuromyelitis-optica-spectrum-disorder-and-six-year-ocrevus-ocrelizumab-data-in-multiple-sclerosis-at-ectrims
  • Cannabidiol Cuts Seizures in Another Rare Epilepsy

    is unlikely to add benefit, but will increase the risk of side effects," he added. This study marks the fifth consecutive positive phase III pivotal trial for Epidiolex, GW Pharma said. To date, Epidiolex is the only CBD product approved by the FDA....

    https://mschristian.org/index.php/blog/cannabidiol-cuts-seizures-in-another-rare-epilepsy
  • Athletico Physical Therapy Opens in Sylvania - P&T Community

    than 5,000 employees. Athletico is committed to our patients and referring physicians through our patient-centric focus, positive work environment, attention to quality and high standard of care. Athletico measures patient outcomes and satisfaction and...

    https://mschristian.org/index.php/blog/athletico-physical-therapy-opens-in-sylvania-p-t-community
  • Stem cell transplant reverses disabling MS-like disease - Medical Xpress

    HSCT. Burt also conducted the first randomized HSCT trials for systemic sclerosis and multiple sclerosis, with strongly positive results. In January 2019, Burt published a randomized study in JAMA showing HSCT reversed neurologic disability and then...

    https://mschristian.org/index.php/blog/stem-cell-transplant-reverses-disabling-ms-like-disease-medical-xpress
  • Can Anti-TNF Drugs Reduce Alzheimer's Risk?

    drugs might affect cognition. A phase II trial of etanercept in Alzheimer's disease published in 2015 showed positive trends but no significant changes in cognition, behavior, or global function. Yet, observational data suggests there might be a link: a...

    https://mschristian.org/index.php/blog/can-anti-tnf-drugs-reduce-alzheimer-s-risk
  • 'We're Just Out of Shape and Weak': What We Heard This Week

    Oncology in Dallas, on a negative breast cancer trial presented at a European cancer meeting that delivered unexpectedly positive results. 2019-10-04T18:00:00-0400 Original link

    https://mschristian.org/index.php/blog/we-re-just-out-of-shape-and-weak-what-we-heard-this-week

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